Article
Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: analgesic efficacy, pharmacokinetics and tolerability.
British journal of clinical pharmacology - 1 Mar 2016
de Vries Marjan, Van Rijckevorsel Dagmar C M, Vissers Kris C P, Wilder-Smith Oliver H G, Van Goor Harry
Abstract excerpt
AIM: We aimed to assess the analgesic efficacy, pharmacokinetics, tolerability and safety of a single dose of Δ9-THC in patients with chronic abdominal pain resulting from chronic pancreatitis (CP). METHODS: This was a randomized, single dose, double-blinded, placebo-controlled, two way crossover study in patients suffering from abdominal pain as result of CP (n = 24), post hoc subdivided into opioid and...
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