Article
Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila.
BMC genomics - 26 Oct 2015
Morozova Tatiana V, Huang Wen, Pray Victoria A, Whitham Thomas, Anholt Robert R H, Mackay Trudy F C
Abstract excerpt
BACKGROUND: Alcohol abuse and alcoholism are significant public health problems, but the genetic basis for individual variation in alcohol sensitivity remains poorly understood. Drosophila melanogaster presents a powerful model system for dissecting the genetic underpinnings that determine individual variation in alcohol-related phenotypes. We performed genome wide association analyses for alcohol sensitivity...
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