Article
Comparative Phosphoproteomics Reveals the Role of AmpC β-lactamase Phosphorylation in the Clinical Imipenem-resistant Strain Acinetobacter baumannii SK17.
Molecular & cellular proteomics : MCP - 1 Jan 2016
Lai Juo-Hsin, Yang Jhih-Tian, Chern Jeffy, Chen Te-Li, Wu Wan-Ling, Liao Jiahn-Haur, Tsai Shih-Feng, Liang Suh-Yuen, Chou Chi-Chi, Wu Shih-Hsiung
Abstract excerpt
Nosocomial infectious outbreaks caused by multidrug-resistant Acinetobacter baumannii have emerged as a serious threat to human health. Phosphoproteomics of pathogenic bacteria has been used to identify the mechanisms of bacterial virulence and antimicrobial resistance. In this study, we used a shotgun strategy combined with high-accuracy mass spectrometry to analyze the phosphoproteomics of the...
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