Article
Phenotypic, Morphological and Adhesive Differences of Human Hematopoietic Progenitor Cells Cultured on Murine versus Human Mesenchymal Stromal Cells.
Scientific reports - 26 Oct 2015
Reichert Doreen, Friedrichs Jens, Ritter Steffi, Käubler Theresa, Werner Carsten, Bornhäuser Martin, Corbeil Denis
Abstract excerpt
Xenogenic transplantation models have been developed to study human hematopoiesis in immunocompromised murine recipients. They still have limitations and therefore it is important to delineate all players within the bone marrow that could account for species-specific differences. Here, we evaluated the proliferative capacity, morphological and physical characteristics of human CD34(+) hematopoietic stem and...
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