Article
Effectiveness of Simeprevir Plus Sofosbuvir, With or Without Ribavirin, in Real-World Patients With HCV Genotype 1 Infection.
Gastroenterology - 1 Feb 2016
Sulkowski Mark S, Vargas Hugo E, Di Bisceglie Adrian M, Kuo Alexander, Reddy K Rajender, Lim Joseph K, Morelli Giuseppe, Darling Jama M, Feld Jordan J, Brown Robert S, Frazier Lynn M, Stewart Thomas G, Fried Michael W, Nelson David R, Jacobson Ira M
Abstract excerpt
BACKGROUND & AIMS: The interferon-free regimen of simeprevir plus sofosbuvir was recommended by professional guidelines for certain patients with hepatitis C virus (HCV) genotype 1 infection based on the findings of a phase 2 trial. We aimed to evaluate the safety and efficacy of this regimen in clinical practice settings in North America. METHODS: We collected demographic, clinical, and virologic data, as well...
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