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Article

Paris-Trousseau: evidence keeps pointing to FLI1.

Blood - 22 Oct 2015

Di Paola Jorge

Abstract excerpt

In this issue of Blood, Stevenson et al describe a family with a homozygous missense mutation in FLI1 that is associated with a platelet phenotype identical to the one observed in Paris-Trousseau syndrome, supporting existing evidence that FLI1 is directly involved in the mechanism of thrombocytopenia observed in this disease.

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Source

Identifiers

PMID: 26494917
DOI: 10.1182/blood-2015-09-667634

Genes

FLI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Paris-Trousseau: evidence keeps pointing to FLI1.PMID 26494917Read ↗

Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1.Semantic proximity Read ↗

FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopeniaSemantic proximity Read ↗

Are thrombophilia more multifactorial than we thought: report of mosaicism for FII G20210A and novel FII T20061C gene variants.Semantic proximity Read ↗

Paris-Trousseau syndrome : clinical, hematological, molecular data of ten new casesSemantic proximity Read ↗

Enrichment of FLI1 and RUNX1 mutations in families with excessive bleeding and platelet dense granule secretion defects.Semantic proximity Read ↗

Update on the inherited platelet disorders.Semantic proximity Read ↗

Hematopoietic transcription factor mutations and inherited platelet dysfunctionSemantic proximity Read ↗

Hematopoietic transcription factor mutations: important players in inherited platelet defects.Semantic proximity Read ↗

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