Article
MicroRNA-encoded behavior in Drosophila.
Science (New York, N.Y.) - 13 Nov 2015
Picao-Osorio Joao, Johnston Jamie, Landgraf Matthias, Berni Jimena, Alonso Claudio R
Abstract excerpt
The relationship between microRNA (miRNA) regulation and the specification of behavior is only beginning to be explored. We found that mutation of a single miRNA locus (miR-iab4/iab8) in Drosophila larvae affects the animal's capacity to correct its orientation if turned upside down (self-righting). One of the miRNA targets involved in this behavior is the Hox gene Ultrabithorax, whose derepression in two...
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