Article
Episodic adaptive diversification of classical swine fever virus RNA-dependent RNA polymerase NS5B.
Canadian journal of microbiology - 1 Dec 2015
Li Yan, Yang Zexiao
Abstract excerpt
Classical swine fever virus (CSFV) is the pathogen that causes a highly infectious disease of pigs and has led to disastrous losses to pig farms and related industries. The RNA-dependent RNA polymerase (RdRp) NS5B is a central component of the replicase complex (RC) in some single-stranded RNA viruses, including CSFV. On the basis of genetic variation, the CSFV RdRps could be clearly divided into 2 major groups...
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