Article
Population genetic testing for cancer susceptibility: founder mutations to genomes.
Nature reviews. Clinical oncology - 1 Jan 2016
Foulkes William D, Knoppers Bartha Maria, Turnbull Clare
Abstract excerpt
The current standard model for identifying carriers of high-risk mutations in cancer-susceptibility genes (CSGs) generally involves a process that is not amenable to population-based testing: access to genetic tests is typically regulated by health-care providers on the basis of a labour-intensive assessment of an individual's personal and family history of cancer, with face-to-face genetic counselling performed...
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