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Article

Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4.

The Journal of allergy and clinical immunology - 1 Jan 2016

Lee Sangmoon, Moon Jin Soo, Lee Cho-Rong, Kim Hye-Eun, Baek Sun-Mi, Hwang Solha, Kang Gyeong Hoon, Seo Jeong Kee, Shin Choong Ho, Kang Hyoung Jin, Ko Jae Sung, Park Sung Gyoo, Choi Murim

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Identifiers

PMID: 26478010
DOI: 10.1016/j.jaci.2015.08.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4.PMID 26478010Read ↗

Underlying CTLA4 Deficiency in a Patient With Juvenile Idiopathic Arthritis and Autoimmune Lymphoproliferative Syndrome Features Successfully Treated With Abatacept-A Case Report.Semantic proximity Read ↗

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A Family with a Novel CTLA4 Haploinsufficiency Mutation and Neurological Symptoms.Semantic proximity Read ↗

A New Variant in CTLA4 Highlights the Heterogeneous Phenotype of CTLA4 Haploinsufficiency.Semantic proximity Read ↗

Molecular landscape of CTLA4 in Mexican patients: variants of unknown significance and clinical correlationSemantic proximity Read ↗

Clinical and Genetic Characteristics of Patients With Novel and Uncertain Significance Variants in CTLA4: A Mexican Cohort.Semantic proximity Read ↗

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.Semantic proximity Read ↗

Therapeutic gene editing of T cells to correct CTLA-4 insufficiencySemantic proximity Read ↗

Intrafamilial clinical variability of CTLA-4 insufficiency hindering early diagnosis.Semantic proximity Read ↗

Neurological manifestation of immune system dysregulation resulting from CTLA-4 receptor mutation: a case report.Semantic proximity Read ↗

CTLA-4: a key regulatory point in the control of autoimmune disease.Semantic proximity Read ↗

Mechanistic Insights into the Inhibition of a Common CTLA-4 Gene Mutation in the Cytoplasmic Domain.Semantic proximity Read ↗

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