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Article

GERV: a statistical method for generative evaluation of regulatory variants for transcription factor binding.

Bioinformatics (Oxford, England) - 15 Feb 2016

Zeng Haoyang, Hashimoto Tatsunori, Kang Daniel D, Gifford David K

Abstract excerpt

MOTIVATION: The majority of disease-associated variants identified in genome-wide association studies reside in noncoding regions of the genome with regulatory roles. Thus being able to interpret the functional consequence of a variant is essential for identifying causal variants in the analysis of genome-wide association studies. RESULTS: We present GERV (generative evaluation of regulatory variants), a novel...

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Identifiers

PMID: 26476779
DOI: 10.1093/bioinformatics/btv565
PMCID: PMC5860000

Genes

FOXA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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