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Molecular Evolution and Epidemiology of Norovirus GII.4 Viruses in the United States

25 Feb 2025

Abstract excerpt

BACKGROUND: Noroviruses are the leading cause of acute gastroenteritis worldwide, with GII.4 Sydney viruses responsible for the majority of infections until 2023. METHODS: To study the evolutionary dynamics of GII.4 noroviruses in the United States (2011-2023), we sequenced and analyzed 406 VP1 and 335 RNA-dependent RNA polymerase sequences submitted to CaliciNet. RESULTS: Time-scale analysis showed that the...

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PMID: 40036172
DOI: 10.1093/infdis/jiaf100

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