Article
FetA Antibodies Induced by an Outer Membrane Vesicle Vaccine Derived from a Serogroup B Meningococcal Isolate with Constitutive FetA Expression.
PloS one - 1 Jan 2015
Sanders Holly, Norheim Gunnstein, Chan Hannah, Dold Christina, Vipond Caroline, Derrick Jeremy P, Pollard Andrew J, Maiden Martin C J, Feavers Ian M
Abstract excerpt
Invasive meningococcal disease causes over 3500 cases each year in Europe, with particularly high incidence among young children. Among serogroup B meningococci, which cause most of the cases, high diversity in the outer membrane proteins (OMPs) is observed in endemic situations; however, comprehensive molecular epidemiological data are available for the diversity and distribution of the OMPs PorA and FetA and...
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