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Article

Higher and lower active circulating VWF levels: different facets of von Willebrand disease.

British journal of haematology - 1 Dec 2015

Casonato Alessandra, Pontara Elena, Morpurgo Margherita, Sartorello Francesca, De Groot Philip G, Cattini Maria G, Daidone Viviana, De Marco Luigi

Abstract excerpt

Most circulating von Willebrand factor (VWF) is normally inactive and incapable of binding platelets, but numerous disorders may modify the proportion of active VWF. We explored active VWF levels in patients with von Willebrand disease (VWD) whose VWF had a higher affinity for platelet glycoprotein (GP)Ib, but different susceptibilities to ADAMTS13 and multimer patterns (9 patients lacking large multimers, 10...

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Share to ADAMTS13 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemostatics

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Share to Platelet Glycoprotein GPIb-IX Complex

Share to Pregnancy Complications, Hematologic

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Source

Identifiers

PMID: 26456374
DOI: 10.1111/bjh.13785

Genes

VWF
ADAMTS13

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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