Article
Analysis of mechanisms involved in reduced susceptibility to ciprofloxacin in Salmonella enterica serotypes Typhi and Paratyphi A isolates from travellers to Southeast Asia.
International journal of antimicrobial agents - 1 Mar 2011
Hassing Robert-Jan, Menezes Godfred A, van Pelt Wilfred, Petit Pieter L, van Genderen Perry J, Goessens Wil H F
Abstract excerpt
Owing to multidrug resistance, quinolones and third-generation cephalosporins are currently used as key antibiotics to combat Salmonella organisms. Therapy failure due to reduced ciprofloxacin susceptibility has been reported in endemic areas, but also in imported disease. Different bacterial res...
Topics
- Amino Acid Substitution
- Anti-Bacterial Agents
- Asia, Southeastern
- Blood
- Ciprofloxacin
- DNA Gyrase
- Drug Resistance, Bacterial
- Genotype
- Humans
- Microbial Sensitivity Tests
- Nalidixic Acid
- Paratyphoid Fever
- Plasmids
- Polymerase Chain Reaction