Article
Biophysical and physiological characterization of ZraP from Escherichia coli, the periplasmic accessory protein of the atypical ZraSR two-component system.
The Biochemical journal - 1 Dec 2015
Petit-Härtlein Isabelle, Rome Kevin, de Rosny Eve, Molton Florian, Duboc Carole, Gueguen Erwan, Rodrigue Agnès, Covès Jacques
Abstract excerpt
The ZraSR system belongs to the family of TCSs (two-component signal transduction systems). In Escherichia coli, it was proposed to participate in zinc balance and to protect cytoplasmic zinc overload by sequestering this metal ion into the periplasm. This system controls the expression of the accessory protein ZraP that would be a periplasmic zinc scavenger. ZraPSR is functionally homologous with CpxPAR that...
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