Article
Thyroid tumorigenesis and molecular markers in thyroid cancer.
Current opinion in oncology - 1 Jan 2010
Kouniavsky Guennadi, Zeiger Martha A
Abstract excerpt
PURPOSE OF REVIEW: The purpose of this review is to provide an update on recent advances in the understanding of thyroid cancer tumorigensis and implications in clinical practice. RECENT FINDINGS: Recent novel and promising findings include additional abnormalities in key pathways associated with thyroid tumorigenesis (RET-Ras-BRAF-MEK; RET-beta-cateinin; TRK-PI3K-AKT; and MDM-p53-PTEN), single-nucleotide...
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