Article
Differences in gluten metabolism among healthy volunteers, coeliac disease patients and first-degree relatives.
The British journal of nutrition - 28 Oct 2015
Caminero Alberto, Nistal Esther, Herrán Alexandra R, Pérez-Andrés Jénifer, Ferrero Miguel A, Vaquero Ayala Luis, Vivas Santiago, Ruiz de Morales José M G, Albillos Silvia M, Casqueiro Francisco Javier
Abstract excerpt
Coeliac disease (CD) is an immune-mediated enteropathy resulting from exposure to gluten in genetically predisposed individuals. Gluten proteins are partially digested by human proteases generating immunogenic peptides that cause inflammation in patients carrying HLA-DQ2 and DQ8 genes. Although intestinal dysbiosis has been associated with patients with CD, bacterial metabolism of gluten has not been studied in...
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