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Article

Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples

1 Jan 2015

Abstract excerpt

BACKGROUND: Usefulness of next-generation sequencing (NGS) in assessing bacteria associated with oral squamous cell carcinoma (OSCC) has been undermined by inability to classify reads to the species level. OBJECTIVE: The purpose of this study was to develop a robust algorithm for species-level classification of NGS reads from oral samples and to pilot test it for profiling bacteria within OSCC tissues. METHODS:...

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PMID: 26426306
DOI: 10.3402/jom.v7.28934

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