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Article

Exacerbation of Charcot-Marie-Tooth type 2E neuropathy following traumatic nerve injury.

Brain research - 19 Nov 2015

Villalón Eric, Dale Jeffrey M, Jones Maria, Shen Hailian, Garcia Michael L

Abstract excerpt

Charcot-Marie-Tooth disease (CMT) is the most commonly inherited peripheral neuropathy. CMT disease signs include distal limb neuropathy, abnormal gait, sensory defects, and deafness. We generated a novel line of CMT2E mice expressing hNF-L(E397K), which displayed muscle atrophy of the lower limbs without denervation, proximal reduction in large caliber axons, and decreased nerve conduction velocity. In this...

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Source

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Identifiers

PMID: 26423936
DOI: 10.1016/j.brainres.2015.09.024
PMCID: PMC5821059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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