Article
MicroRNA-574 is involved in cognitive impairment in 5-month-old APP/PS1 mice through regulation of neuritin.
Brain research - 19 Nov 2015
Li Fei, Wei Gang, Bai Ye, Li Yunjun, Huang Fengyuan, Lin Jian, Hou Qiuke, Deng Rudong, Zhou Jian Hong, Zhang Sai Xia, Chen Dong Feng
Abstract excerpt
Alzheimer's disease (AD) is the most common form of dementia in the elderly. The recent evidence in AD research suggests that alterations in the microRNA (miRNA) could contribute to risk for the disease. However, little is understood about the roles of miRNAs in cognitive impairment of early Alzheimer's disease (AD). Here, we used 5-month-old APP/PS1 mice, which mimic many of the salient features of the early...
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