Article
Low Vitamin D Levels and Genetic Polymorphism in the Vitamin D Receptor are Associated with Increased Risk of Statin-Induced Myopathy.
Basic & clinical pharmacology & toxicology - 1 Mar 2016
Ovesjö Marie-Louise, Skilving Ilona, Bergman Peter, Rane Anders, Ekström Lena, Björkhem-Bergman Linda
Abstract excerpt
The main aim of this study was to test the hypothesis whether 25-hydroxyvitamin D (25OHD) levels <50 nmol/L at baseline could predict statin-induced myopathy during the course of treatment. In addition, we analysed the association between a genetic polymorphism in the vitamin D receptor (VDR) and the risk of statin-induced myopathy. We used serum samples from a prospective, observational study in statin-treated...
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