Article
Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology.
Oncotarget - 20 Oct 2015
Patel Sandip P, Schwaederle Maria, Daniels Gregory A, Fanta Paul T, Schwab Richard B, Shimabukuro Kelly A, Kesari Santosh, Piccioni David E, Bazhenova Lyudmila A, Helsten Teresa L, Lippman Scott M, Parker Barbara A, Kurzrock Razelle
Abstract excerpt
Tumor sequencing has revolutionized oncology, allowing for detailed interrogation of the molecular underpinnings of cancer at an individual level. With this additional insight, it is increasingly apparent that not only do tumors vary within a sample (tumor heterogeneity), but also that each patient's individual tumor is a constellation of unique molecular aberrations that will require an equally unique...
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