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Towards consistent generation of pancreatic lineage progenitors from human pluripotent stem cells

30 Sept 2015

Abstract excerpt

Human pluripotent stem cells can in principle be used as a source of any differentiated cell type for disease modelling, drug screening, toxicology testing or cell replacement therapy. Type I diabetes is considered a major target for stem cell applications due to the shortage of primary human beta cells. Several protocols have been reported for generating pancreatic progenitors by in vitro differentiation of...

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PMID: 26416676
DOI: 10.1098/rstb.2014.0365

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