Article
Host specificity in the diversity and transfer of lsa resistance genes in group B Streptococcus.
The Journal of antimicrobial chemotherapy - 1 Dec 2015
Douarre Pierre-Emmanuel, Sauvage Elisabeth, Poyart Claire, Glaser Philippe
Abstract excerpt
OBJECTIVES: In group B Streptococcus (GBS), cross-resistance to lincosamides, streptogramin A and pleuromutilins (LSAP) is mediated by the acquisition of lsa genes. Here, we characterized the diversity, mobility and ecology of lsa genes in this species. METHODS: lsa variants were systematically identified by BLAST searches in the genomes of 531 GBS strains from different hosts and geographical origins. The...
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