Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.

doi:10.1038/ncomms5544

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Article

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.

Nature communications - 4 Aug 2014

Da Cunha Violette, Davies Mark R, Douarre Pierre-Emmanuel, Rosinski-Chupin Isabelle, Margarit Immaculada, Spinali Sebastien, Perkins Tim, Lechat Pierre, Dmytruk Nicolas, Sauvage Elisabeth, Ma Laurence, Romi Benedetta, Tichit Magali, Lopez-Sanchez Maria-José, Descorps-Declere Stéphane, Souche Erika, Buchrieser Carmen, Trieu-Cuot Patrick, Moszer Ivan, Clermont Dominique, Maione Domenico, Bouchier Christiane, McMillan David J, Parkhill Julian, Telford John L, Dougan Gordan, Walker Mark J, Holden Matthew T G, Poyart Claire, Glaser Philippe

Abstract excerpt

Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal of the digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial neonatal infections in Europe and North America during the 1960s. Due to the lack of epidemiological and genomic data, the reasons for this emergence are unknown. Here we show by comparative genome analysis and phylogenetic reconstruction of 229...

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PMID: 25088811
DOI: 10.1038/ncomms5544
PMCID: PMC4538795

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