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Zearalenone Induces Apoptosis and Autophagy in a Spermatogonia Cell Line

17 Feb 2022

Abstract excerpt

species, and it is a potent estrogenic metabolite that affects reproductive health in livestock and humans. In this study, the molecular mechanisms of toxicity and cell damage induced by ZEN in GC-1 spermatogonia (spg) cells were evaluated. Our results showed that cell viability decreased and apoptosis increased in a dose-dependent manner when GC-1 spg cells were exposed to ZEN. In addition, the key proteins...

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PMID: 35202175
DOI: 10.3390/toxins14020148

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