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Article

Paired-like Homeodomain Transcription factor 2 expression by breast cancer bone marrow disseminated tumor cells is associated with early recurrent disease development.

Breast cancer research and treatment - 1 Oct 2015

Pillai Sreeraj G, Dasgupta Nupur, Siddappa Chidananda M, Watson Mark A, Fleming Timothy, Trinkaus Kathryn, Aft Rebecca

Abstract excerpt

The presence of disseminated tumor cells (DTCs) in the bone marrow (BM) of breast cancer patients is prognostic for early relapse. In the present study, we analyzed the gene expression profiles from BM cells of breast cancer patients to identify molecular signatures associated with DTCs and their relevance to metastatic outcome. We analyzed BM from 30 patients with stage II/III breast cancer by gene expression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26400846
DOI: 10.1007/s10549-015-3576-z
PMCID: PMC4589549

Genes

PITX2
DKK4
NKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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