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Article

Kernel machine SNP set analysis finds the association of BUD13, ZPR1, and APOA5 variants with metabolic syndrome in Tehran Cardio-metabolic Genetics Study.

Scientific reports - 13 May 2021

Masjoudi Sajedeh, Sedaghati-Khayat Bahareh, Givi Niloufar Javanrouh, Bonab Leila Najd Hassan, Azizi Fereidoun, Daneshpour Maryam S

Abstract excerpt

Metabolic syndrome (MetS) is one of the most important risk factors for cardiovascular disease. The 11p23.3 chromosomal region plays a potential role in the pathogenesis of MetS. The present study aimed to assess the association between 18 single nucleotide polymorphisms (SNPs) located at the BUD13, ZPR1, and APOA5 genes with MetS in the Tehran Cardio-metabolic Genetics Study (TCGS). In 5421 MetS affected and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33986338
DOI: 10.1038/s41598-021-89509-5
PMCID: PMC8119714

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