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Article

Single Nucleotide Polymorphisms in the BDNF, VDR, and DNASE 1 Genes in Dry Eye Disease Patients: A Case-Control Study.

Investigative ophthalmology & visual science - 1 Sept 2015

Hallak Joelle A, Tibrewal Sapna, Mohindra Neil, Gao Xiaoyi, Jain Sandeep

Abstract excerpt

PURPOSE: To identify single nucleotide polymorphisms (SNPs) in the brain-derived neurotrophic factor (BDNF), vitamin D receptor (VDR), and DNASE1 genes that may be associated with dry eye disease (DED), and determine whether this association varies by the presence of depression. METHODS: A case-control study was performed with 64 DED cases and 51 controls. We collected 2 mL of saliva following a routine eye exam....

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Source

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Identifiers

PMID: 26393465
DOI: 10.1167/iovs.15-17036
PMCID: PMC5102496

Genes

BDNF
VDR
DNASE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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