Article
Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2016
Brown Patrick J, Roose Steven P, Zhang Jun, Wall Melanie, Rutherford Bret R, Ayonayon Hilsa N, Butters Meryl A, Harris Tamara, Newman Anne B, Satterfield Suzanne, Simonsick Eleanor M, Yaffe Kristine
Abstract excerpt
BACKGROUND: Inflammation, slow gait, and depression individually are associated with mortality, yet little is known about the trajectories of these measures, their interrelationships, or their collective impact on mortality. METHODS: Longitudinal latent class analysis was used to evaluate trajectories of depression (Center for Epidemiologic Studies Depression ≥ 10), slow gait (<1.0 m/s), and elevated inflammation...
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