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Article

Complexity and diversity of F8 genetic variations in the 1000 genomes.

Journal of thrombosis and haemostasis : JTH - 1 Nov 2015

Li J N, Carrero I G, Dong J F, Yu F L

Abstract excerpt

BACKGROUND: Hemophilia A (HA) is an X-linked bleeding disorder caused by deleterious mutations in the coagulation factor VIII gene (F8). To date, F8 mutations have been documented predominantly in European subjects and in American subjects of European descent. Information on F8 variants in individuals of more diverse ethnic backgrounds is limited. OBJECTIVES: To discover novel and rare F8 variants, and to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26383047
DOI: 10.1111/jth.13144
PMCID: PMC4928474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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