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The spectrum of FVIII gene variants detected by next generation sequencing in 236 Chinese non-inversion hemophilia A pedigrees.

Thrombosis research - 1 Jun 2021

Chen Juanjuan, Li Qiang, Lin Sheng, Li Fenxia, Huang Limin, Jin Wangjie, Yang Xu, Li Yihong, Li Kun, Xiong Yufeng, Fan Dongmei, Zheng Lei, Luo Dixian, Li Liyan, Yang Xuexi

Abstract excerpt

INTRODUCTION: The reported variants of hemophilia A are mainly from European subjects and American subjects of European descent, and limited data are available from more diverse ethnic backgrounds. This study was performed to identify the causative variants in a large HA cohort from Chinese population. MATERIALS AND METHODS: A total of 236 HA pedigrees were included. Molecular analysis of F8 gene was performed...

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PMID: 33706050
DOI: 10.1016/j.thromres.2021.02.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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