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Article

Genetic engineering, high resolution mass spectrometry and nuclear magnetic resonance spectroscopy elucidate the bikaverin biosynthetic pathway in Fusarium fujikuroi.

Fungal genetics and biology : FG & B - 1 Nov 2015

Arndt Birgit, Studt Lena, Wiemann Philipp, Osmanov Helena, Kleigrewe Karin, Köhler Jens, Krug Isabel, Tudzynski Bettina, Humpf Hans-Ulrich

Abstract excerpt

Secondary metabolites of filamentous fungi can be highly bioactive, ranging from antibiotic to cancerogenic properties. In this study we were able to identify a new, yet unknown metabolite produced by Fusarium fujikuroi, an ascomycetous rice pathogen. With the help of genomic engineering and high-performance liquid chromatography (HPLC) coupled to high resolution mass spectrometry (HRMS) followed by isolation and...

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PMID: 26382642
DOI: 10.1016/j.fgb.2015.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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