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Article

High yield exogenous protein HPL production in the Bombyx mori silk gland provides novel insight into recombinant expression systems.

Scientific reports - 15 Sept 2015

Wang Huan, Wang Lu, Wang Yulong, Tao Hui, Yin Weimin, SiMa Yanghu, Wang Yujun, Xu Shiqing

Abstract excerpt

The silk gland of Bombyx mori (BmSG) has gained significant attention by dint of superior synthesis and secretion of proteins. However, the application of BmSG bioreactor is still a controversial issue because of low yields of recombinant proteins. Here, a 3057 bp full-length coding sequence of Hpl was designed and transformed into the silkworm genome, and then the mutant (Hpl/Hpl) with specific expression of Hpl...

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Identifiers

PMID: 26370318
DOI: 10.1038/srep13839
PMCID: PMC4570194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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