Article
Ligneous membranitis in Scottish Terriers is associated with a single nucleotide polymorphism in the plasminogen (PLG) gene.
Animal genetics - 1 Dec 2015
Ainsworth Stuart, Carter Stuart, Fisher Claire, Dawson Jenna, Makrides Loria, Nuttall Tim, Mason Sarah L
Abstract excerpt
Ligneous membranitis (LM) is a rare chronic inflammatory condition of the mucous membranes associated with plasminogen (encoded by PLG) deficiency in affected humans and dogs. In human, the condition is genetic in nature with numerous mutations and polymorphisms in PLG identified in affected individuals and related family members. The condition is uncommonly reported in dogs and, to date, no genetic studies have...
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