Article
An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer.
Oncotarget - 20 Oct 2015
Agostini Marco, Janssen Klaus-Peter, Kim Il-Jin, D'Angelo Edoardo, Pizzini Silvia, Zangrando Andrea, Zanon Carlo, Pastrello Chiara, Maretto Isacco, Digito Maura, Bedin Chiara, Jurisica Igor, Rizzolio Flavio, Giordano Antonio, Bortoluzzi Stefania, Nitti Donato, Pucciarelli Salvatore
Abstract excerpt
INTRODUCTION: Colorectal cancer is the third most common cancer in the world, a small fraction of which is represented by locally advanced rectal cancer (LARC). If not medically contraindicated, preoperative chemoradiotherapy, represent the standard of care for LARC patients. Unfortunately, patients shows a wide range of response rates in which approximately 20% has a complete pathological response, whereas in 20...
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