Article
Rate of telomere shortening and metabolic and cardiovascular risk factors: A longitudinal study in the 1934–44 Helsinki Birth Cohort Study
18 Aug 2015
Abstract excerpt
INTRODUCTION: Leucocyte telomere length (LTL) is associated with age-related health outcomes, but only few longitudinal studies have assessed changes in LTL in an ageing population. METHODS: A total of 1,082 subjects from the Helsinki Birth Cohort Study (born 1934-1944), undergoing two clinical visits ∼10 years apart, were studied. Relative LTL was measured twice by quantitative real-time PCR. Simple and multiple...
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