Undifferentiated pleomorphic sarcoma with co-existence of KRAS/PIK3CA mutations.

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Article

Undifferentiated pleomorphic sarcoma with co-existence of KRAS/PIK3CA mutations.

International journal of clinical and experimental pathology - 1 Jan 2015

Li Bingcheng, Li Li, Li Xiaoying, Wang Yuanyuan, Xie Yuwen, Liu Chunxia, Li Feng

Abstract excerpt

BACKGROUND: Undifferentiated pleomorphic sarcoma (UPS), previously known as malignant fibrous histiocytoma, comprises a series of high-grade soft tissue sarcomas, which fail to exhibit any specific line of differentiation by using currently available ancillary techniques. Studies on gene mutation screening occurring in UPS are rarely conducted. In this study, we described a case of UPS and analyzed its mutation...

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Source

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Identifiers

PMID: 26339434
PMCID: PMC4555762

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.