Article
New substitution models for rooting phylogenetic trees.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 26 Sept 2015
Williams Tom A, Heaps Sarah E, Cherlin Svetlana, Nye Tom M W, Boys Richard J, Embley T Martin
Abstract excerpt
The root of a phylogenetic tree is fundamental to its biological interpretation, but standard substitution models do not provide any information on its position. Here, we describe two recently developed models that relax the usual assumptions of stationarity and reversibility, thereby facilitating root inference without the need for an outgroup. We compare the performance of these models on a classic test case...
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