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Article

Assessing Uncertainty in the Rooting of the SARS-CoV-2 Phylogeny.

Molecular biology and evolution - 13 Apr 2021

Pipes Lenore, Wang Hongru, Huelsenbeck John P, Nielsen Rasmus

Abstract excerpt

The rooting of the SARS-CoV-2 phylogeny is important for understanding the origin and early spread of the virus. Previously published phylogenies have used different rootings that do not always provide consistent results. We investigate several different strategies for rooting the SARS-CoV-2 tree and provide measures of statistical uncertainty for all methods. We show that methods based on the molecular clock...

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Identifiers

PMID: 33295605
DOI: 10.1093/molbev/msaa316
PMCID: PMC7798932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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