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Article

Asexual sporulation facilitates adaptation: The emergence of azole resistance in Aspergillus fumigatus.

Evolution; international journal of organic evolution - 1 Oct 2015

Zhang Jianhua, Debets Alfons J M, Verweij Paul E, Melchers Willem J G, Zwaan Bas J, Schoustra Sijmen E

Abstract excerpt

Understanding the occurrence and spread of azole resistance in Aspergillus fumigatus is crucial for public health. It has been hypothesized that asexual sporulation, which is abundant in nature, is essential for phenotypic expression of azole resistance mutations in A. fumigatus facilitating subsequent spread through natural selection. Furthermore, the disease aspergilloma is associated with asexual sporulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26315993
DOI: 10.1111/evo.12763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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