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Article

AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects

27 Aug 2015

Abstract excerpt

Autophagy is a major molecular mechanism that eliminates cellular damage in eukaryotic organisms. Basal levels of autophagy are required for maintaining cellular homeostasis and functioning. Defects in the autophagic process are implicated in the development of various age-dependent pathologies including cancer and neurodegenerative diseases, as well as in accelerated aging. Genetic activation of autophagy has...

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PMID: 26312549
DOI: 10.1080/15548627.2015.1082023

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