Article
Using Genetics to Identify Hereditary Colorectal Polyposis and Cancer Syndromes in Your Patient.
Current gastroenterology reports - 1 Oct 2015
Macaron Carole, Heald Brandie, Burke Carol A
Abstract excerpt
The majority of patients with colorectal polyps and cancer do not have a Mendelian cause of the disease. Age, lifestyle, and environmental factors interact with complex genetic traits to contribute to the etiology. However, approximately 5-10 % of patients with colorectal cancer (CRC) and more than 40 % of patients meeting specific clinical features of the hereditary polyposis syndromes have a discoverable,...
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