Article
[THE EFFECTIVENESS OF ERADICATION IN PATIENTS WITH PEPTIC ULCER DISEASE ASSOCIATED WITH HELICOBACTER PYLORI, DEPENDING ON THE GENOTYPE OF THE DRUGMETABOLISM OF PROTON PUMP INHIBITORS].
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology - 1 Jan 2015
Elokhina E V, Kostenko M B, Livzan M A, Scalskiy S V
Abstract excerpt
One of the most likely causes of the lack of effectiveness of eradication therapy of peptic ulcer associated with Helicobacter pylori, is a feature of omeprazole metabolism by cytochrome CYP2C19. The paper work presents evidence that the rate of reduction of the clinical picture and the likelihood of scarring ulcers and eradication rates higher in patients slow metabolizers of omeprazole.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.