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Article

A Rapid, High-Quality, Cost-Effective, Comprehensive and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.

Circulation research - 11 Sept 2015

Wilson Kitchener D, Shen Peidong, Fung Eula, Karakikes Ioannis, Zhang Angela, InanlooRahatloo Kolsoum, Odegaard Justin, Sallam Karim, Davis Ronald W, Lui George K, Ashley Euan A, Scharfe Curt, Wu Joseph C

Abstract excerpt

RATIONALE: Thousands of mutations across >50 genes have been implicated in inherited cardiomyopathies. However, options for sequencing this rapidly evolving gene set are limited because many sequencing services and off-the-shelf kits suffer from slow turnaround, inefficient capture of genomic DNA, and high cost. Furthermore, customization of these assays to cover emerging targets that suit individual needs is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26265630
DOI: 10.1161/CIRCRESAHA.115.306723
PMCID: PMC4568077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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