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Article

The common PNPLA3 variant p.I148M is associated with liver fat contents as quantified by controlled attenuation parameter (CAP).

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2016

Arslanow Anita, Stokes Caroline S, Weber Susanne N, Grünhage Frank, Lammert Frank, Krawczyk Marcin

Abstract excerpt

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is becoming the most prevalent liver disorder. The PNPLA3 (adiponutrin) variant p.I148M has been identified as common genetic modifier of NAFLD. Our aim was to assess the relationships between genetic risk and non-invasively measured liver fat content. METHODS: Hepatic steatosis was quantified by transient elastography, using the controlled attenuation...

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Source

Identifiers

PMID: 26264356
DOI: 10.1111/liv.12937

Genes

PNPLA3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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