Article
Genetic variants of numb gene were associated with elevated total cholesterol level and low density lipoprotein cholesterol level in Chinese subjects, in Xinjiang, China.
Diagnostic pathology - 12 Aug 2015
Abudoukelimu Mayila, Fu Zhen-Yan, Xiang Yang, Ma Yi-Tong, Zhu Qing, Abudu Minawaer, Adi Dilare, Yang Yi-Ning, Li Xiao-Mei, Xie Xiang, Liu Fen, Chen Bang-Dang
Abstract excerpt
BACKGROUND: Hypercholesterolemia is one of the most common risk factors for Coronary Artery Disease (CAD), which is the leading cause of death worldwide. As Numb is an important regulating factor regarding intestinal cholesterol absorption and plasma cholesterol level, the aim of the present study is to investigate the relationship between human Numb gene polymorphism and cholesterol level in Chinese subjects....
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