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Article

A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).

International journal of molecular sciences - 6 Aug 2015

Luchetti Andrea, Ciafrè Silvia Anna, Murdocca Michela, Malgieri Arianna, Masotti Andrea, Sanchez Massimo, Farace Maria Giulia, Novelli Giuseppe, Sangiuolo Federica

Abstract excerpt

Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder and the leading genetic cause of death in infants. Despite the disease-causing gene, survival motor neuron (SMN1), encodes a ubiquitous protein, SMN1 deficiency preferentially affects spinal motor neurons (MNs), leaving the basi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Motor Neurons

Share to Muscular Atrophy, Spinal

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Source

Open in PubMed Open full text

Identifiers

PMID: 26258776
DOI: 10.3390/ijms160818312
PMCID: PMC4581247

Genes

SMN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26258776-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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