Article
[Band 3 deficiency as a cause of hereditary spherocytosis].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jul 2015
Wada Hideho, Suemori Shin-Ichiro, Nakanishi Hidekazu, Sugihara Takashi
Abstract excerpt
Band 3 protein accounts for the largest percentage of whole erythrocyte membrane proteins. Abnormalities in this protein are closely associated with pathologies including hereditary spherocytosis (HS), Southeast Asian ovalocytosis and distant renal tubular acidosis. Currently, EMA binding capacity measurement in erythrocytes is the most useful screening test for diagnosing HS. We have also demonstrated reduced...
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